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"Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms"

The groups most likely to develop B12-related hair and skin changes are the same ones at risk for deficiency generally: vegans and vegetarians, adults over 50, people on long-term metformin or proton pump inhibitors, anyone who's had bariatric surgery, and people on GLP-1 protocols whose reduced appetite has significantly lowered their overall nutrient intake for an extended period

Based on evidence from clinical studies, the USPHS, AAP, and ACOG recommend a folic acid intake of 0.4 mg/day PO from food and/or supplements in females during the child-bearing years, and 0.6 mg PO daily throughout pregnancy

For comparison, semaglutide alone produced 14.9% weight loss, cagrilintide alone produced 11.5%, and placebo delivered just 3%