George, K
A 35-day Chronic Unpredictable Mild Stress (CUMS) protocol was implemented (detailed in Figure S2) 40,41,42,43,44 , involving 33 male Wistar rats divided into a non-stressed control group receiving saline (NaCl 0.9%, 1.5 ml) (Control + Saline, n = 9) and two CUMS-exposed groups receiving daily intraperitoneal injections of either saline (CUMS + Saline, n = 9) or 10 mg/kg fluoxetine (CUMS + Fluoxetine, n = 15
The serum has a stable formulation, is easy to apply, and comes in dark glass packaging, preventing oxidation
256 In contrast, the herpes simplex virus (HSV) preferentially infects astrocytes and oligodendrocytes, whereas microglia become reactive and neuroprotective through release of inflammatory mediators, such as interferon-, TNF-, IL-1, IL-6 and IL-8, RANTES and chemokine CXCL10