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Optimizing the substituent on the benzimidazole nitrogen proved a fruitful approach to improve potency without detrimentally impacting physiochemical properties, with smaller, more polar groups preferred
Many users alternate nights retinoid one evening, GHK-Cu the next or apply retinoid at night and copper peptide in the morning
Reduced shedding is often the first measurable improvement
Zhou L, Konopleva M, Andreeff M
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