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If its used for a medical procedure, it wont cause lasting effects but if its frequently used recreationally, it can seriously affect B12 levels, cause a deficiency and impair healthy functioning of the body (Campdesuner et al., 2020

Additionally, GHK-Cu increases the expression of lysyl oxidase, the enzyme responsible for cross-linking collagen and elastin fibers, thereby reinforcing the three-dimensional architecture of the extracellular matrix

Like CRBN, FBXO3 scored highly in these screens, suggesting that it may be similarly well disposed to proximity pharmacology 92,93