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Additionally, stress hormones adrenaline and cortisol make the heart beat faster and constrict blood vessels in preparation for the fight-or-flight response

Frail older people may be particularly vulnerable to nutritional deficiencies if appetite suppression is excessive, potentially contributing to unintentional weight loss and sarcopenia

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Fast forward to the 2010s, when it was now undergoing clinical trials to be approved as a treatment for female sexual dysfunction, which can be ironic considering it was a male scientist decades earlier who accidentally discovered its effects on sexual performance after injecting himself with it