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Obesity Clinical Development Pipeline MoA Abbreviations: GLP-1 RA GLP-1 receptor agonist(s)
Later medications like semaglutide and tirzepatide are engineered versions - chemically modified human GLP-1 with structural changes that prevent degradation and extend half-life from seconds to days
Michael Marmor, MD, and I, among others, published detailed guidelines for managing this problem back in 2016, on behalf of the American Academy of Ophthalmology
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