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This historic test consisted, in its first step, of taking an oral dose of radiolabelled vitamin B 12 , followed by quantitation of the vitamin in the patient's urine over a 24-hour period via measurement of the radioactivity

What starts as minor discomfort can progress to severe pain, stiffness, and even permanent disability if left untreated

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Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP