type 2 diabetes and semaglutide Semaglutide-Mediated Remodeling of Adipose Tissue in Diabetes: Molecular Mechanisms Beyond Glycemic Control The Beneficial Side Effects of

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As a central component of the cell-to-cell and intracellular lactate shuttles, lactate ensures efficient energy distribution from its production sites such as glycolytic muscle fibers to oxidative tissues, including heart, brain, and oxidative muscle fibers, where it serves as a primary fuel for mitochondrial oxidative phosphorylation [233, 234]