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La evidencia reciente motiv un cambio del enfoque teraputico glucocntrico al cardiorrenometablico con la inclusin en las reco mendaciones internacionales de nuevas terapias con beneficios cardiovasculares y renales Contribucin del artculo al conocimiento actual Se describen los efectos directos e indirectos de los agonistas del receptor del pptido similar al glucagn tipo 1 (GLP-1) segn los estudios clnicos y de la vida real, que confirman sus efectos beneficiosos sobre la funcin renal en diabetes e introducen la expectativa de los estudios en curso con objetivos renales
It is important to note that at the beginning of each study, researchers should start with a low daily dose and increase the liraglutide dosage over the course of five weeks to prevent side effects
From a research perspective, this titration process was essential for two reasons
However, they are approximately 40% less effective in comparison to injections
