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However, it is imperative to note that findings from animal models cannot be directly extrapolated to clinical trials in humans
While the GLP-1 pathway is familiar from medications like semaglutideknown for slowing gastric emptying and increasing satietythis treatment adds GIP activation, further boosting insulin response and potentially supporting fat metabolism
Two critical factors in this association are pro-inflammatory cytokines and adipokines
1 Side effects and contraindications Currently, patients with a history of pancreatitis, kidney disease, active gall bladder disease, medullary thyroid cancer, multiple endocrine neoplasia, and any allergy to this medicine are advised against taking these medications
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