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A pivotal consideration is that the weight loss achieved with these medications directly addresses the primary pathophysiological driver of MASLD

The derivation from native hGH provides biological plausibility: the C-terminal region of growth hormone has been known since the 1990s to possess independent lipolytic activity separate from the growth-promoting effects mediated by intact GH and IGF-1 signaling

Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified

Loti Labs provides high-purity AOD 9604 manufactured under GMP conditions in USA facilities