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Complex medical cases: Frequent monitoring needs suit traditional clinics ($450-$700/month) better than telehealth, despite higher costs

Long-term maintenance therapy is usually necessary to sustain weight loss benefits

It should not be used in people with a personal or family history of medullary thyroid carcinoma (MTC) or those with Multiple Endocrine Neoplasia syndrome type 2 (MEN2) due to a boxed warning about thyroid C-cell tumors based on animal studies