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[4] Together, the obesity and diabetes trials give retatrutide the broadest Phase 2 metabolic dataset of the two compounds, and the program has extended into hepatic (liver-fat / MASLD) and cardiometabolic questions that reflect the glucagon arms biology

Retatrutide, development code LY3437943, is Eli Lilly's investigational triple hormone receptor agonist

At 50 mg to 200 mg per dose, the high injection volume requires intramuscular (IM) administration or splitting the dose across multiple subcutaneous sites

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