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Perimenopause and hormonal decline are among the most common and least recognized drivers of new-onset GI symptoms in women over 35 bloating, IBS-like symptoms, and increased gut reactivity often emerge alongside hormonal shifts

Prescription drugs are often used effectively for getting UC under control

Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

- Neurological support: Explored for its effects on nerve healing and neuroinflammation in animal models