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All methods involving human material were carried out in accordance with the Declaration of Helsinki guidelines and regulations
The dose-response curve was measured with a characterised, assayed, sterile clinical product of known peptide content
Tirzepatide is primarily excreted by the kidneys, so reduced renal function could theoretically affect its pharmacokinetics and efficacy (Velenosi and Urquhart, 2014)
B12 shots are typically given in the muscle of the upper arm (deltoid) or the hip (gluteal muscle)
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