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This research provides additional evidence to suggest that discontinuing GLP-1 agonists at least 14 days before total joint replacement surgery is optimal to reduce the risk of delayed emergence from anesthesia, aspiration events, aspiration pneumonitis and conversion to intubation, said John R

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Researchers think that any type of rapid weight loss, including from weight loss drugs like GLP-1s, can lead to muscle loss in addition to fat loss

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