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Conditions such as Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Fibromyalgia (FM), and Gulf War Syndrome (GWS) are examples of these chronic illnesses that are triggered by different factors but share overlapping clinical symptoms, in particular profound fatigue (see Figure 1)

W.JonesA.1988Metabolites of procainamide and practolol inhibit complement components C3 and C4.2512(April 1988),323326,0264-6021 100

Inflammation worsens liver damage and promotes the development of cirrhosis and its complications [79, 80, 103, 104]

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