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If you cannot tolerate a maintenance dose of 2.4 mg once weekly, consider with your healthcare provider about decreasing the maintenance dose to 1.7 mg once a week
This is usually when side effects are most likely, not because semaglutide itself is problematic, but because the combined receptor activity from overlapping drugs can temporarily amplify gastrointestinal effects
Given the pivotal role of growth hormone in fat metabolism, this elevation becomes crucial for achieving effective fat loss
But that day, if it ever comes, is likely many years away
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