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MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Limited human safety data Animal toxicology shows wide therapeutic window Injection-site reactions reported anecdotally Known interactions Anticoagulants (theoretical, due to angiogenic activity unstudied) Contraindications Active malignancy (theoretical, due to angiogenic mechanism) Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Placed on FDA Category 2 of the 503A bulks list (September 2023 update), barring compounding pharmacies from preparing it under section 503A
Research suggests these applications may give insights into preserving muscle function across various challenge conditions
Leveraging these enzymes for targeted anti-tumor therapy holds the advantage of precision targeting, minimal damage to healthy cells and reduced toxic side effects, thereby enhancing and reversing tumor drug resistance
Cells 10:3294
