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Studies have shown that IF significantly enhances GH secretion and elevates insulin-like growth factor binding protein 1 (IGFBP1) levels up to fivefold [42], thereby modulating IGF-1 bioavailability and enhancing autophagy, lipolysis, and muscle preservation [42, 43]

Together, these complementary approaches create opportunities to move beyond descriptive studies toward predictive reprogramming of flavonoid regulatory networks under complex environmental conditions

Retrieved from Kraftson, A., & Griauzde, D