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A recent systematic review and meta-analysis of seven trials (including SURPASS 1-5) covering 6,609 participants found that tirzepatide (5mg, 10mg, and 15mg) resulted in dose-dependent reductions in HbA1c levels compared to placebo, with mean differences ranging from -1.62% to -2.06%
This will not disappoint, you will notice the difference as soon as possible and its a crazy difference
Reactions are more likely during the intensive loading phase simply because the doses are close together
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