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Additionally, SCFAs are vital in determining the differentiation, quantity, and secretory capabilities of enteroendocrine cells, which affects both the baseline and stimulus-induced neuroendocrine responses [119,120]

In the SURPASS-2 clinical trial, Mounjaro demonstrated greater HbA1c reductions compared to semaglutide 1 mg, with mean reductions of up to 2.3% (25 mmol/mol) from baseline at the 15 mg dose

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