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2 Pharmacotherapy in obesity and BED: a difficult legacy Pharmacological treatment of obesity has historically faced significant limitations, with many agents demonstrating only moderate efficacy and a high incidence of adverse effects [24, 25]
Semaglutide was approved as Ozempic in 2017 for type 2 diabetes, then at a higher dose as Wegovy in 2021 specifically for obesity, with clinical trials showing around 15% average body weight loss via slowing how quickly the stomach empties
van Ruiten CC, Smits MM, Kok MD, Sern EH, van Raalte DH, Kramer M, et al
Peripheral heart disease makes it harder for people with diabetes to walk long distances
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