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This transient elevation is attributable to the immaturity of carnitine transport and utilization mechanisms in preterm infants (38, 39)
treatment with interferon-beta, glatiramer acetate or corticosteroids within the 30 days before screening
However, the fundamental constraint remains: as an agonist of the impaired receptor itself, its mechanism is intrinsically compromised, which may limit efficacy and necessitate robust validation
Adults experiencing moderate or severe gastrointestinal adverse events while on GLP-1 therapy were more likely to stop treatment whether they had type 2 diabetes (HR = 1.38
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