new indications for glp-1 drugs GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety. https://ja.ma/3JZg8l3 GLP-1 Pipeline Update: February 2025

Phase Moderate range Daily dose 40-80 mcg/day Frequency Once daily Notes Diminishing returns commonly reported above ~50-60 mcg/day

Possible side effects include: Mild nausea or stomach discomfort Headache or restlessness Muscle cramps A slight fish-like odor (in rare cases) Individuals who are pregnant, nursing, or have thyroid or kidney conditions should consult a healthcare professional before starting supplementation

Yet, analysis of data from NHANES 2003-2018, a US national cross-sectional survey of 39,438 adults, found an inverse association between selenium intake and stroke, with daily intakes of 105 g/day linked to the lowest stroke risk (93)

Consultation with dermatologists or skincare professionals A personalised assessment is vital