9 The STEP-HFpEF DM randomised controlled trial enrolled 616 patients with obesity (BMI 30 kg/m 2 ) and both HFpEF (LVEF 40%) and T2D
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I have participated in a study which showed levels of glutathione within the cells increased dramatically by the use of oral supplementation
Tolerability Issues : The adverse events with the GLP-1-based therapies are primarily gastrointestinal and include nausea, vomiting, constipation, or diarrhea [82], leading to meaningful discontinuation rates that limit real-world effectiveness