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While these medications help regulate appetite and metabolism, long-term success requires ongoing commitment to healthy eating and physical activity

While FDA-approved domestic generics remain blocked by patent protections until at least 2031, US patients still have legitimate options through Medicare programs, manufacturer savings offers, and Health Canada-approved generic semaglutide available from licensed Canadian pharmacies with a valid prescription

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Patients with pre-existing gastrointestinal conditions, such as inflammatory bowel disease or previous bowel surgery, should have a lower threshold for seeking advice