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Vitamin B12 injections are the most common and effective way to prevent and treat a deficiency

Ten-year Registry Data Gyeong Mi Heo, Mi Hee Kim, Jin Hwan Kim, Young Soo Rho, Woon Geon Shin The Korean Journal of Gastroenterology.2016

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Mechanistic studies have revealed that altered expression of iron metabolism-related proteins (including GPX4, FTH1, TfR1, and HO-1), accumulation of lipid peroxidation products, and disruption of antioxidant defense systems (particularly the Nrf2/GPX4 pathway) are central to ferroptosis progression in cardiac tissue