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This is not based on drug clearance: the drug is gone from plasma within hours
Molar concentration conversion (for receptor pharmacology assays that require nanomolar concentrations): Molar concentration (M) = [mg/mL] / [MW in g/mol] 1,000,000 For cagrilintide (MW approximately 4,550 g/mol): - 1 mg/mL = approximately 220 M stock From a 220 M stock, you can dilute to nanomolar concentrations needed for receptor binding assays with simple serial dilution
Front Cell Dev
On a detachable-needle syringe it can approach 70100 L which at 5 mg/mL represents roughly 0.350.5 mg of peptide left behind per draw
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