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Weight change may be one benefit, but medication choice also depends on heart health, kidney function, hypoglycemia risk, side effects, and cost
The same is true for oral micronized progesterone
Keep the approach specific, evidence-aware and calm
Of interest, although liver-derived IGF-I has endocrine effects on extrahepatic tissues, there are only few data regarding local effects of this hormone in the liver[87] probably due to the very low amount of IGF-I receptors on the hepatocytes membrane[46, 88, 89]
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