Theyre caused by water retention fluctuations, hormone adjustments, sodium intake changes, menstrual cycles (for women), and metabolic adaptation
In addition, for PCOS patients with insulin resistance (IR), metformin can effectively reduce hyperglycemia and hyperinsulinemia, improve ovulatory function, reduce androgen levels, control weight and waist circumference gain, and mitigate the risks of diabetes mellitus and cardiovascular disease (Notaro and Neto, 2022)
Canadian trial sites have been established in Vancouver, Toronto, Montreal, and Calgary, with additional locations possible as enrollment continues
Creatine supplementation does not influence hair growth or hormone levels even after three months of usage, undermining theories of its potential link to hair loss