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Native IGF-1 has a frustrating pharmacokinetic limitation: it binds tightly to a family of IGF binding proteins (IGFBPs, particularly IGFBP-3) that sequester it in circulation and keep its free half-life to roughly 15-20 minutes
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References Heffernan, M., Summers, R.J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W.J., & Ng, F.M
Although the effectiveness of metabolism can be limited by factors such as liver damage and medications, nothing will speed up detoxification rates, including sleep or drinking water
This might mean you need shots more often
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