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Patients should stop the medication and contact their healthcare provider immediately if they experience: Severe or persistent abdominal pain (especially if radiating to the back), which could indicate pancreatitis Persistent vomiting preventing adequate fluid intake Signs of dehydration (dark urine, dizziness, reduced urination) Yellowing of skin or eyes (jaundice) or pale stools Unexplained fever Severe diarrhoea lasting more than 48 hours Treatment continuation is reviewed regularly, with decisions based on efficacy, tolerability, and ongoing clinical need

For individuals exploring powerful and clinically proven options beyond semaglutide, Tirzepatide may be an excellent choice

Traditionally, the background event rates in the population are based on cross-sectional or prevalence studies

If diarrhea persists beyond a few days at any dose level, it may indicate that the dose escalation happened too quickly