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Weight reduction triggers adaptive changes in hunger and satiety hormones and energy expenditure, which favor weight regain, Neff says

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Balancing Blood Sugar Glucose Sensitivity Cellularly: Understand the importance of glucose sensitivity at the cellular level and the role of the Glut 4 receptor in facilitating glucose uptake for energy production

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JAMA (2016) 315(9):898907

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some case reports noted concerns over exenatide and semaglutide worsening depressive symptoms, and a larger study suggested a slightly increased risk of suicidal behaviour with liraglutide

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