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It works by reducing appetite and hunger, slowing the release of food from the stomach so the patient feels full longer, to aid in weight loss. Dr
Current investigations are focused on understanding whether NNMT inhibition might influence cancer progression or aggressiveness
Pharmacokinetic studies demonstrated approximately 38% oral bioavailability and blood-brain barrier penetration, unusual for a peptide-based compound and attributable to Dihexa's small size (504.66 Da) and hydrophobic modifications
Anecdotal reports from Phase 2 participants suggest that nausea severity is higher when dosing occurs in the early morning on an empty stomach, possibly because fasting amplifies the compound's gastric-slowing effect
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