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Other NMDA antagonists (i.e., MK801 and memantine) do not have the same anesthetic, analgesic, and antidepressant effects of KET, leaving open the question of its mechanisms of action (Robu and Lavandhomme, 2019)
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In mammals, ferroptosis has been implicated in diverse pathologies, including neurodegenerative diseases, stroke, traumatic brain injury and kidney degeneration, as well as in carcinogenesis, where it may exert a tumor-suppressor function
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