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3.1 Riboflavin transporter deficiency Riboflavin transporter deficiency (RTD)historically termed BrownVialettoVan Laere or Fazio-Londe syndromeis a rare, early-onset motor neuron disease that couples the biochemistry of riboflavin with overt neurodegeneration ( SLC52A2 or SLC52A3 abrogate membrane uptake of riboflavin, precipitating secondary FMN/FAD depletion in metabolically demanding neurons and glia ( Mechanistic work in patient fibroblasts and iPSC-derived motor neurons confirms that transporter mutations collapse intracellular FMN/FAD pools, impair respiratory-chain flux and trigger neurite loss
Archived from the original on 28 October 2007
For busy professionals looking to take their skincare to the next level, pairing red light therapy with other proven ingredients like vitamin C, retinol, and hyaluronic acid can create a powerhouse routine
Nash P, Zhao N (2020) 1000 at 1000: particulate-reinforced metal matrix composites
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