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Diabetologia 65(Suppl 1):S288S288 Samms RJ, Zhang G, He W et al (2022) Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue
The short peptides in these medications are chemically modified so that they last longer in the body and work better than the naturally occurring GLP-1 hormone
Finally, to assess functional relevance, we treated HCD-fed mice with rotenone, a mitochondrial complex I inhibitor, and evaluated survival following CLP-induced sepsis
doi: 10.1177/15353702211060513 5
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