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"So that seems to happen, and we see it with bariatric [obesity-management] surgery too." Rubino says that some people can regain weight after quitting semaglutide, but still retain some of the metabolic health benefits achieved while taking the drug, such as improved blood sugar control

While effective, it can cause side effects ranging from mild to serious, including oral thrush, headaches, sore throat, hoarseness, and rare adrenal suppression

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GLP-1 receptor agonists like semaglutide and tirzepatide have transformed obesity treatment by delivering impressive weight loss