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Key Takeaways Vitamin B12 injections are essential for treating deficiencies

This does not exempt it from the systemic safety considerations that apply to IV glutathione, but the route and dose context are meaningfully different

Pontes et al., 2020)

In detail, ROS are involved in disturbing antioxidant defenses, the mitochondria, microtubule, ion channels, and biomolecular functions, as well as inducing neuroinflammation, demyelination, and neuronal apoptosis in the process of PIPN (Areti et al., 2014)

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