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Treatment with once-weekly cagrilintide (0.16, 0.30, 0.60, 1.2, 2.4, and 4.5 mg) in combination with semaglutide 2.4 mg for 20 weeks was not associated with an increase in adverse events compared with placebo in combination with semaglutide 2.4 mg, with no unexpected safety or tolerability findings
Because this study was observational rather than a randomized clinical trial, were a lot more worried that what we are seeing might be confounding rather than a true causal effect
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