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This observation is the main scientific basis for believing any mucosal route (including nasal) could work, but it is an inference, not a measurement
Both medications independently cause nausea and stomach upset, so combining them amplifies these side effects and raises concerns about ulcers and bleeding
Bolontrade MF, Zhou RR, Andreeff M , Weidner DA, Kleinerman ES
If eligible, the provider recommends an individualized dosage and discusses lifestyle guidance to support sustainable weight loss
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