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Start low for general health, and scale up if you are targeting specific outcomes like skin radiance or intense immune support
After 2Y of treatment, liver volumes in most patients were 1.25 multiples of normal (mean reductions: 30% in ASCEND, 49% in ASCEND-Peds, 30% reduction in Phase 1b with 44% reduction after 6.5Y) and mean HDL cholesterol had increased 65% in ASCEND, 137% in ASCEND-Peds, and 115% in Phase 1b (171% increase at 6.5Y)
The implications are significant: Repurposing an inexpensive, widely available drug Targeting the intersection of inflammasome activation, TP53 dysfunction, and neoplastic risk Potential relevance for disorders ranging from CAPS and histiocytosis to MDS and beyond We urgently need more translational work on this underappreciated molecule
Your body requires vitamin B12 to work more effectively
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