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During exercise, this decreased thirst perception can lead to inadequate hydration

However, they do not substitute for validated stability data, and adherence to the authorised protocol remains the primary obligation

Based on this finding, two incretin-based medications were developed: (1) DPP-4 inhibitors that increase the concentration of GLP-1 by inhibiting it [22], and (2) GLP-1RAs, which act directly on the GLP-1 receptor [23]

However, studies have shown that some individuals may lose around 5% of their body weight within the initial four weeks, but this can depend on factors such as the dose and the patients overall health