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Medical Community Response The emerging evidence of adverse gastric effects associated with these drugs has prompted the medical community to reassess their safety profile

Since GLP-1 medications themselves can cause gastrointestinal side effects including nausea and altered bowel habits, individuals without a gallbladder may experience a compounding effect that requires careful dietary management and potentially slower dose titration according to the product's SmPC guidance

NICE NG246 Weight Management Guidance 7

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