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Similar to GLP-1(7-37), exenatide also acts as an agonist for GLP-1(7-37), but shows resistance to DPP-4 degradation and has a lower renal clearance rate in human, making exenatide the first successfully developed GLP-1 drug [6]
The synthetic Ac-SDKP fragment (TB-500) replicates the actin-binding activity of the larger protein and has been studied in preclinical models of cardiac injury, skeletal muscle repair, and skin wound healing
10.1007/s12016-021-08899-6 Clin Rev Allergy Immunol
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