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As such, they do not fit well into the Class I/II designation for neuroectodermal neoplasia discussed above
Quantitative PCR (qPCR) was performed on the StepOnePlus Real-Time PCR System (Applied Biosystems, Thermo Fisher Scientific, MA, USA)
Newer medicine options, including the sodium-glucose cotransport 2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists, have been shown to protect the heart and reduce the risk of many specific heart-related outcomes for people with type 2 diabetes
However, this method is unable to discriminate between GLP-1R clustering at the plasma membrane versus bona fide endocytosis events, although these are intrinsically linked, with the former occurring rapidly after ligand stimulation as a precursor to uptake into clathrin-coated vesicles (Buenaventura et al ., 2019)
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