There is one important protection worth noting: "If you are not a candidate or approved for GLP-1 medication, your subscription will be cancelled, and we will work with you to find another solution." The company also states elsewhere that "if not deemed appropriate, you will be immediately refunded." The practical takeaway: the billing structure is quarterly, cancellation is available but fees already paid are described as non-refundable, and there is a minimum commitment period described in the terms
Randomization was conducted using an interactive web response system, assigning participants in a 6:1 ratio to one of several treatment arms: once-weekly subcutaneous Cagrilintide administered in doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo
Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity (STEP 3 (Wadden et al., JAMA , 2021))
For those with IBS-D (diarrhoea-predominant IBS), there can be some improvements in bowel urgency and/or frequency