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During antiviral responses, the aspartate-argininosuccinate shunt pathway generates fumarate, which enhances type I interferon production via MAVS protein succination (59)
To advance our understanding of PD, it is important to clearly define which aspects of the disease we aim to explore and how our research question aligns with the chosen model
However, clinical benefits are conferred after at least three years [13,14,15]
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