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Doses of 8 mg and above add exposure after the curve has begun to flatten
2 (0.2%) placebo-treated patients during clinical trials of semaglutide injection used for weight management
The SURMOUNT-5 head-to-head trial directly compared Zepbound to Wegovy, with results published in The New England Journal of Medicine: The addition of GIP receptor activation unlocks approximately 6% additional fat loss compared to GLP-1-only medications, while also helping preserve muscle mass better
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